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Zytaze

Capsules that enhance the effects and duration of Botox


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What is Zytaze®?

Zytaze® provides nutritional support to enhance the effectiveness of botulinum toxin injections in cosmetic procedures. Formulated with a unique blend of organic zinc and phytase to increase zinc absorption, Zytaze® has been found to extend the duration of botulinum toxin injections by almost 25%*

  • Improve effects
  • Speeds up impact
  • Increases duration

What is Botox (botulinum toxin)?

Botulinum toxin is a protein derived from Clostridium botulinum that helps stop muscle spasms. Muscle spasms are caused by chemical messages sent to the muscles from nerves. These messages tell the muscles to contract (tighten up). Botulinum toxin blocks these messages.

What are the ingredients in Zytaze®?

Each capsule contains Zinc as Zinc Citrate 25 mg and Phytase 500 mg. Other ingredients include: Silicon Dioxide, Magnesium Stearate, and Microcrystalline Cellulose.

What is phytase?

Phytase is an enzyme that effectively breaks down phytates, a group of phosphate-containing compounds which tightly bind zinc in the intestinal tract and prevent zinc absorption. Phytates are found in whole grain breads, whole-wheat products, many cereals, soy, oats, legumes (including peas, peanuts and peanut butter), beans, corn, nuts, rice, and other foods as well.
If I take more zinc and phytase, will it increase the effectiveness of my botulinum toxin injections?
More of a good thing is not necessarily better. Too much zinc can cause gastrointestinal symptoms of nausea, vomiting, diarrhoea, and stomach pain as well as dizziness, kidney dysfunction, anemia, and decreased immune function. Too much zinc may actually DECREASE the effect of botulinum toxins. Too much phytase on a regular basis may cause too much zinc absorption resulting in the previously mentioned side effects. Consuming a controlled amount of zinc and phytase prior to and at the time of receiving botulinum toxin injections is recommended to enhance effects without the risk of zinc toxicity.

When do I take Zytaze®?

Two capsules daily for four days prior to and on the day of receiving botulinum toxin injections. Each package contains 10 capsules. Zytaze® may be taken during meals or snacks, but avoid taking Zytaze® within two hours of medications and/or supplements.

Why should I take Zytaze® before my next botulinum toxin treatment?

To be effective, botulinum toxin requires the presence of zinc and current dietary trends suggest that many patients are zinc deficient. Zytaze® is specially formulated with a unique patent-pending combination of organic zinc and phytase, an enzyme that aids zinc absorption thereby enhancing the effectiveness of botulinum toxin injections.

How is Zytaze® supplied?

Zytaze® is supplied in a blister pack of 10 clear, hard-shell capsules containing a white/off white crystalline powder

How it works

Botulinum toxins represent a family of some of the most potent naturally occurring toxins in the world, and because of their ability to inhibit muscle contractions, these toxins have been widely used in the treatment of many involuntary movement disorders and cosmetic procedures. However, to be effective, each toxin molecule must be associated with a molecule of zinc. Without zinc, the otherwise powerful botulinum toxins have little or no effect.

Botulinum toxins are made by bacteria in a laboratory, collected, purified, and then processed into a fine, dry powder. Oddly enough, if zinc is added to the toxin during processing, the toxin’s potency is greatly diminished. To be effective, Botulinum toxins must find and bind zinc in human tissues after being injected. If a person has inadequate amounts of zinc in their tissues, then the botulinum toxin will have a significantly decreased effect.

Patient-specific change in duration of botulinum toxin effect compared to no supplementation following pre-injection supplementation with laculose placebo or 50 mg zinc citrate and 3,000 U phytase (Zytaze® Supplementation).

Patient-specific change in duration of botulinum toxin effect compared to no supplementation following pre-injection supplementation with laculose placebo or 50 mg zinc citrate and 3,000 U phytase (Zytaze® Supplementation).

Zinc levels are increased by eating zinc, and although numerous foods such as poultry, beef, pork, eggs, whole grains, beans, and legumes are relatively rich in zinc, many of these as well as other foods simultaneously block zinc absorption. Zinc supplements found in local naturefood, or vitamin stores are an alternative resource, but some forms of zinc are much better absorbed than others, and taking a poorly absorbed form of zinc can compete for absorption with better zinc available through foods, which can be worse than taking no zinc at all.

There are a number of reasons why zinc absorption may be inhibited. Blocked absorption is one, and perhaps the biggest culprits responsible are phytates, a group of phosphate-containing compounds that tightly bind zinc in the intestinal track and prevent zinc absorption. As little as 0.26 grams of phytate will inhibit the absorption of 50 mg of pure zinc. Phytates are found in whole grain breads, whole-wheat products, many cereals, soy, oats, legumes (including peas, peanuts, and peanut butter), beans, corn, nuts, and rice. Unfortunately, many of the foods rich in zinc also contain phytates, so it can be very difficult to increase and monitor zinc levels through diet alone.

Zytaze® is specially formulated with a unique patent-pending combination of highly bioavailable, organic zinc along with phytase (an enzyme that effectively breaks down phytates) to maximize zinc absorption, thereby enhancing the effectiveness of botulinum toxin injections.

A recent pilot study*, utilizing Zytaze® demonstrated that increasing zinc levels for 4 days prior to a planned botulinum toxin injection resulted in an increase in both the treatment effect as well as duration. Importantly, the study included blepharospasm, hemifacial spasm and cosmetic patients.This study suggests that using Zytaze® may lead to fewer toxin injections at a lower dose and with less treatment-to-treatment variability in effect.

In the completed formal study* consisting of 77 patients, Zytaze® again demonstrated a significant increase in the effect of botulinum toxin injections. In fact, the duration of effect increased from 23.6% in the pilot study to be 30% in the completed formal study.

*Koshy JC, Sharabi SE, Feldman EM, Hollier LH, Patrinely JR, Soparkar CNS. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol 2012 Apr 1; 11(4):507-12.

Contact to discuss

Please call Kate on 07919 200 456 to book an appointment or an aesthetic consultation to discuss any queries or concerns that you may have.